An increasing number of young adults are suffering ischemic stroke, which is the most common stroke type. Tobacco use is on the rise among young adults. It is already established that the more young women smoke the greater their stroke risk; however, little is known about young men's stroke risk from smoking.

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'The key takeaway from our study on men younger than 50 is 'the more you smoke, the more you stroke,' said lead study author Janina Markidan, B.A., a medical student at the University of Maryland School of Medicine in Baltimore. Researchers studied 615 young men (age 15-49) who had a stroke in the prior three years. Researchers compared the men with stroke to 530 healthy men in the same age range. They also categorized participants as never smokers, former smokers and current smokers. Current smokers were divided into groups based on the number of cigarettes smoked daily, 1 to 10, 11 to 20, 21 to 39 or 40 or more.

Researchers found: • Men who smoked were 88 percent more likely to have a stroke than men who never smoked. • Among current smokers, men who smoked fewer than 11 cigarettes daily were 46 percent more likely to have a stroke than those who never smoked. • But the heavier smokers, smoking at least two packs a day, were nearly 5 times, more likely to have a stroke than those who never smoked. 'The goal is to get these young men to stop smoking, however if they can smoke fewer cigarettes it could help reduce their stroke risk,' Markidan said. Researchers did not record the concurrent use of other tobacco products which could have affected results. They also did not control for factors such as alcohol consumption, physical activity or recall bias.

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However, similar findings in a Swedish study, suggested that there was not a major effect from recall bias. Co-authors are John W. Cole, M.D., M.S.; Carolyn A. Cronin, M.D., Ph.D.; Jose G.

Merino, M.D., M. Phil.; Michael S. Phipps, M.D.; Marcella A. Wozniak, M.D., Ph.D.; and Steven J. Kittner, M.D., M.P.H. Author disclosures are on the manuscript.

The Department of Veterans Affairs, the Centers for Disease Control and Prevention and the National Institutes of Health funded the study.

At dinner, seeing Warrington take his share with a great deal of gusto, did not scruple about helping himself any more, rather to the disappointment of honest Lowton. When the dinner was over, Warrington asked Arthur where he was going. 'I thought of going home to dress, and hear Grisi in Norma,' Pen said. 'Are you going to meet anybody there?' Pen said, 'No—only to hear the music,' of which he was fond. 'You had much better come home and smoke a pipe with me,' said Warrington,—'a very short one.

Come, I live close by in Lamb Court, and we'll talk over Boniface and old times.' They went away; Lowton sighed after them.

He knew Warrington was a baronet's son, and he looked up with simple reverence to all the aristocracy. Pen and Warrington became sworn friends from that night.

Warrington's cheerfulness and jovial temper, his good sense, his rough welcome, and his never-failing pipe of tobacco, charmed Pen, who found it more pleasant to dive into shilling taverns with him, than to dine in solitary state amongst the silent and polite frequenters of the Polyanthus. Ere long Pen gave up the lodgings in St. James's, to which he had migrated on quitting his hotel, and found it was much more economical to take up his abode with Warrington in Lamb Court, and furnish and occupy his friend's vacant room there. For it must be said of Pen, that no man was more easily led than he to do a thing, when it was a novelty, or when he had a mind to it. And Pidgeon, the youth, and Flanagan, the laundress, divided their allegiance now between Warrington and Pen.